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Press Release “Development and publication of the zebrafish brain gene expression database”

Jun 4, 2024

Dr Towako Kajiyama,CBS Laboratory for Systems Molecular Ethology (at the time of the research,  currently Graduate School of Life Sciences, Tohoku University), Drs Hiroyaya Itoga and Shuichi Ohnami, BDR Laboratory for Developmental Dynamics, et. al. have developed the “AZEBEX”, a database of gene expression in the zebrafish brain. We mapped 38 neuropeptide genes and excitatory/inhibitory neuronal marker genes in the brains of zebrafish and published them as a gene expression atlas and database. Based on the expression data obtained, we proposed a way to divide the brain regions and analysed the similarities with the mouse brain, and found that the gene expression patterns of zebrafish and mice are very similar in several brain regions.

The results are expected not only to contribute to the future development of neuroscience research using zebrafish, but also to provide important clues in the search for common brain functions across species.

 

RIKEN Press Release (Jun 4, 2024)

Development and publication of the zebrafish brain gene expression database

*Article is written in Japanese only.